For example, to Subscript 2 in mathematical equation like this, you need to: select 2 Hit Ctrl + = on your keyboard to remove Subscript, simply select Subscript and Hit Ctrl + = shortcut again to remove it to Subscript in Excel with shortcuts, you need to use a combination of keyboard shortcuts. That means that you do have to use the insert equation feature. This shortcut works in Microsoft Word and PowerPoint to quickly create subscripts.
Subscript shortcuts are Ctrl + = on PC and Ctrl + Cmd + on Mac.